Publication Date
1998
Journal or Book Title
Phosphorous Sulfur and Silicon and the Related Elements
Abstract
Consumption of Se-enriched plants or yeast-based nutritional supplements is reported to reduce the risk of cancer. Separation and identification of natural organoselenium compounds in these plants is essential to understand the basis for their biological activity. Earlier work suggests that plants convert inorganic selenium in the soil or growth medium into organoselenium compounds, such as selenoamino acids, following a route similar to the sulfur assimilatory pathway. To separate and detect selenoamino acids in plant extracts, we employ ion pair LC with an inductively coupled plasma mass spectrometer (ICP-MS) detector and capillary GC with an atomic emission detector (AED), for underivatized and derivatized compounds, respectively. Volatile selenium compounds, such as those found in human garlic breath, have been analyzed using GCAED. Results involving Se-enriched garlic and yeast-based nutritional supplements are presented.
Pages
1-10
Volume
136, 137 & 138
License
UMass Amherst Open Access Policy
Recommended Citation
Block, Eric; Bird, Susan; Tyson, Julian; Uden, Peter C.; Zhang, Xing; and Denoyer, Eric R., "The Search for Anticarcinogenic Organoselenium Compounds from Natural Sources" (1998). Phosphorous Sulfur and Silicon and the Related Elements. 1436.
Retrieved from https://scholarworks.umass.edu/chem_faculty_pubs/1436