Off-campus UMass Amherst users: To download dissertations, please use the following link to log into our proxy server with your UMass Amherst user name and password.
Non-UMass Amherst users, please click the view more button below to purchase a copy of this dissertation from Proquest.
(Some titles may also be available free of charge in our Open Access Dissertation Collection, so please check there first.)
Multi-scale analysis for microscopic models in materials science and cell biology
Abstract
In Part I, we study the effects of random fluctuations included in microscopic models for phase transitions, to macroscopic interface flows. We first derive asymptotically a stochastic mean curvature evolution law from the stochastic Ginzburg-Landau model and develop a corresponding level set formulation. Secondly we demonstrate numerically, using stochastic Ginzburg-Landau and Ising algorithms, that microscopic random perturbations resolve geometric and numerical instabilities in the event of non-uniqueness in the corresponding deterministic flow. In Part II, we analyze the effects of random local linker length variability on the global morphology of a very long, linear, homogeneous chromatin fiber that is modelled as a diffusion process which is parametrized by arclength under a suitable spatial re-scaling. We obtain a Fokker-Planck equation for the process whose solution, a probability density function describes the folding. ^
Subject Area
Biology, Cell|Mathematics|Engineering, Materials Science
Recommended Citation
Alvin Thong-Juak Kho,
"Multi-scale analysis for microscopic models in materials science and cell biology"
(January 1, 2000).
Electronic Doctoral Dissertations for UMass Amherst.
Paper AAI9978515.
http://scholarworks.umass.edu/dissertations/AAI9978515