Dissertations from 2024
POSTSYNAPTIC CHANGES IN INHIBITORY SIGNALING ARE NOT NECESSARY FOR EXPERIENCE-DEPENDENT MAINTENANCE OF THE VISUAL PATHWAY, Parag S. Juvale and Parag S. Juvale, Molecular and Cellular Biology
INVESTIGATING THE ESCAPE MECHANISM OF SRE BEARING MRNA TRANSCRIPTS DURING VIRAL HOST SHUTOFF, Daniel MacVeigh-Fierro, Molecular and Cellular Biology
Visual Experience is Necessary for Maintenance but not Development of Lateral Inhibition in Superior Colliculus, Christine M. Otfinoski, Molecular and Cellular Biology
Dissertations from 2023
Establishing Personalized Medicine in Fabry Disease Through Functional Analysis of Disease Mutants, Efecan Aral, Molecular and Cellular Biology
PROTEIN TRAFFICKING IN THE ENDOPLASMIC RETICULUM MEDIATED BY A TPR-CONTAINING ADAPTER PROTEIN, Nathan P. Canniff, Molecular and Cellular Biology
THE GENOMIC DYNAMICS OF FERMENTED FOOD MICROBES, Katherine Chacón-Vargas, Molecular and Cellular Biology
Characterizing the roles of the variable linker and hub domains in CaMKII activation, Noelle Dziedzic, Molecular and Cellular Biology
Intracellular Delivery of siRNA Therapeutics through Polymer Nanoassemblies, Taewon Jeon, Molecular and Cellular Biology
Investigating Signaling Mechanisms of Neuronal Maturation and Synapse Function Using Human Induced Neuronal Cells, Danny B. McSweeney, Molecular and Cellular Biology
Investigating Conformational Isomers of Protein Oligomers using Native Mass Spectrometry, Stacey G. Nash, Molecular and Cellular Biology
TRANSCRIPTIONAL REGULATION OF BONE FORMATION, MECHANOSENSING, AND EVOLUTION, Emily R. Tetrault, Molecular and Cellular Biology
Molecular analysis of phase separation on the plant cell surface, Robert Yvon, Molecular and Cellular Biology
Dissertations from 2022
CHARACTERIZING THE MULTIFACETED ROLES OF THE PROTEASOMAL DEUBIQUITINASE UCH37 IN PROTEOSTASIS, Heather A. Bisbee, Molecular and Cellular Biology
Synthesis and targeting of the bacterial cell wall, Alam García-Heredia, Molecular and Cellular Biology
Genetic and Environmental Regulation of Plant Growth, Kirk J-M MacKinnon, Molecular and Cellular Biology
Principles of AAA+ Proteases, Samar Mahmoud, Molecular and Cellular Biology
CHEMICAL BIOLOGY APPROACHES FOR TRACKING AND MANIPULATION OF MACROPHAGE PHENOTYPES, Javier A. Mas Rosario, Molecular and Cellular Biology
Exposure to Endocrine Disrupting Chemicals and the Effects on Inflammation and Mammary Tumor Progression, Stephanie Morin, Molecular and Cellular Biology
STRUCTURAL STUDIES OF CaMKII ACTIVATION AND OLIGOMERIZATION, Can Özden, Molecular and Cellular Biology
Human Saposin B Ligand Binding and Presentation to α-Galactosidase A, Thomas K. Sawyer, Molecular and Cellular Biology
EXTRACELLULAR MATRIX STIFFNESS AS A CUE TO SHAPE PHENOTYPIC EVOLUTION OF TRIPLE NEGATIVE BREAST CANCER, Ning-Hsuan Tseng, Molecular and Cellular Biology
Dissertations from 2021
Substrate selection in endoplasmic reticulum protein quality control, Ben Adams, Molecular and Cellular Biology
MECHANISMS OF MITOTIC CHECKPOINT SILENCING BY THE DISORDERED KINETOCHORE PROTEIN SPC105, Margaux Audett, Molecular and Cellular Biology
DISCOVERING MECHANISMS DRIVING ADAPTIVE EVOLUTION IN THE CROSS-KINGDOM FUNGAL PATHOGEN FUSARIUM OXYSPORUM, Dilay Hazal Ayhan, Molecular and Cellular Biology
BIOCHEMICAL STUDIES OF FABRY DISEASE AND FUCOSIDOSIS, Cameron Butova, Molecular and Cellular Biology
PHARMACOLOGICAL CHAPERONING OF HUMAN LYSOSOMAL NEURAMINIDASE 1, Di Chu, Molecular and Cellular Biology
RAPID CELL PHENOTYPING USING ARRAY-BASED SENSORS: APPLICATIONS IN CANCER STEM CELL THERAPY AND HIGH-CONTENT SCREENING, Yingying Geng, Molecular and Cellular Biology
Mechanistic Insights into Diverse Protease Adaptor Functions, NATHAN J. KUHLMANN, Molecular and Cellular Biology
It Takes a Village to Build a Brain: Defining the Heterogenous Glial and Neural Crest Contributions to Zebrafish Forebrain Development and Neurogenesis, Jake Schnabl, Molecular and Cellular Biology
Understanding how CaMKII holoenzyme dynamics facilities activation-triggered subunit exchange, Ana P. Torres-Ocampo, Molecular and Cellular Biology
APPLYING GENOME-WIDE ASSOCIATION IN THE FUNGAL PATHOGEN ASPERGILLUS FUMIGATUS TO IDENTIFY THE GENETIC CONTRIBUTORS OF ANTIFUNGAL SENSITIVITY AND THERMOTOLERANCE, Shu Zhao, Molecular and Cellular Biology
Dissertations from 2020
Exploring Signatures of Host-Microbial Coevolution Between Colonic Bifidobacterium Species and Host Dietary Carbohydrates, Korin Albert, Molecular and Cellular Biology
Defining the let-7 microRNA-mediated molecular mechanisms regulating T cell differentiation, Constance C. Angelou, Molecular and Cellular Biology
INTER-INDIVIDUAL VARIATION IN RESPONSE TO ESTROGEN AND IMPLICATIONS FOR BREAST CANCER RISK, Amye L. Black, Molecular and Cellular Biology
TPR-CONTAINING PROTEINS CONTROL PROTEIN ORGANIZATION AND HOMEOSTASIS FOR THE ENDOPLASMIC RETICULUM, Jill Bradley-Graham, Molecular and Cellular Biology
Dissecting regulatory mechanisms of quorum sensing pathways in Bacillus subtilis, Patrick Hill, Molecular and Cellular Biology
Multivesicular Release in Hair Cell Ribbon Synapses in the Bullfrog Amphibian Papilla, Fuu-Jiun Hwang, Molecular and Cellular Biology
ROLES OF RECN DNA REPAIR PROTEIN AND PRIA DNA HELICASE IN MAINTAINING GENOMIC INTEGRITY OF ESCHERICHIA COLI K-12, Anastasiia N. Klimova, Molecular and Cellular Biology
Hedgehog Signaling (Hh/Gli) Regulates Neurogenesis in the Zebrafish Hypothalamus, Ira Male, Molecular and Cellular Biology
A Rational Design Approach to Developing Second Generation Fabry Disease Treatments, Matthew Metcalf, Molecular and Cellular Biology
Improved Molecular Diagnostics for Soil-Transmitted Helminths, Nils Pilotte, Molecular and Cellular Biology
CHARACTERIZING ADAPTIVE NON-CODING CHANGES IN THE REGULATION OF HUMAN GENE EXPRESSION, Jason Pizzollo, Molecular and Cellular Biology
REDOX SIGNALING IN THE ZEBRAFISH EMBRYO AND IMPLICATIONS FOR ENDOCRINE PANCREAS MORPHOGENESIS, Archit Rastogi, Molecular and Cellular Biology
Liver Kinase B1 isoform expression as a regulator of T cell phenotypic stability, Heather Sherman, Molecular and Cellular Biology
Engineering mesothelin-binding proteins as targeted cancer diagnostics and therapeutics, Allison Rita Sirois, Molecular and Cellular Biology
ACCESSORY GENES CONTRIBUTE TO REWIRING THE TRANSCRIPTIONAL NETWORK IN FUSARIUM OXYSPORUM, He Yang, Molecular and Cellular Biology
The Lon protease integrates protein quality control with DNA damage responses in Caulobacter crescentus, Rilee D. Zeinert, Molecular and Cellular Biology
DE-CODING THE IMPACT OF EVOLVED CHANGES IN GENE EXPRESSION AND CELLULAR PHENOTYPE ON PRIMATE EVOLUTION, Trisha Zintel, Molecular and Cellular Biology
Dissertations from 2019
ENGINEERING OF AN ANTIBODY-CONJUGATED NANOGEL PLATFORM FOR TARGETED DRUG DELIVERY TO T LYMPHOCYTES, Mine Canakci, Molecular and Cellular Biology
ENHANCING NANOPORE BASED BIOSENSENING TECHNOLOGY USING PORE FORMING PROTEINS, Christina M. Chisholm, Molecular and Cellular Biology
CHARACTERIZATION OF β-2-MICROGLOBULIN PRE-AMYLOID OLIGOMERS AND THEIR ROLE IN AMYLOID INHIBITION, Tyler M. Marcinko, Molecular and Cellular Biology
ENVIRONMENTAL RISK FACTORS FOR INFLAMMATORY BOWEL DISEASE: TRICLOSAN AND OTHER CONSUMER ANTIMICROBIALS, Katherine Z. Sanidad, Molecular and Cellular Biology
Let-7 MiRNAs Program The Fate Of CD8 T Cells, Alexandria Wells, Molecular and Cellular Biology
Dissertations from 2018
TARGETED LOCALIZATION OF MICROTUBULE-SEVERING ENZYMES TO CREATE NEW LOCAL TOOLS TO STUDY CELL DIVISION, Siddheshwari Advani, Molecular and Cellular Biology
MECHANISM OF REGULATION OF KINESINS EG5 AND KIF15 BY TPX2, Sai Keshavan Balchand, Molecular and Cellular Biology
EXAMINING sHSP-SUBSTRATE CAPTURE AND CHAPERONE NETWORK COORDINATION THROUGH CROSS-LINKING, Keith Ballard, Molecular and Cellular Biology
REGULATION OF EXPRESSION OF THE T CELL WC1 CO-RECEPTOR AND PATTERN RECOGNITION RECEPTOR MULTIGENE FAMILY, Payal Damani-Yokota, Molecular and Cellular Biology
Structural studies of acid alpha glucosidase and Pompe disease, Derrick Deming, Molecular and Cellular Biology
The Role of the Metallochaperone HypA in the Acid Survival and Activities of Nickel Enzymes in Helicobacter pylori, Heidi Hu, Molecular and Cellular Biology
IDENTIFYING FUNCTIONAL COMPONENTS OF THE ENDOPLASMIC RETICULUM QUALITY CONTROL AND DEGRADATION FACTOR EDEM1, Lydia Lamriben, Molecular and Cellular Biology
Motor Protein Regulation in Mammalian Mitosis, Barbara Mann, Molecular and Cellular Biology
EPIGENETIC REGULATION OF GENOMIC IMPRINTING DURING EARLY MAMMALIAN EMBRYONIC DEVELOPMENT, Chelsea Marcho, Molecular and Cellular Biology
Cadherin-11 Ectodomain Signaling in Cranial Neural Crest Migration, Ketan Mathavan, Molecular and Cellular Biology
STUDIES OF DYNEIN ANCHORING PROTEIN IN BUDDING YEAST SACCHAROMYCES CEREVISIAE, Safia Omer, Molecular and Cellular Biology
Defining and Manipulating the Function of Protein Kinase C-theta in Graft versus Host Responses, Emrah Ilker Ozay, Molecular and Cellular Biology
EXTRINSIC AND INTRINSIC FACTORS IN LIVER DEVELOPMENT, Amrita Palaria, Molecular and Cellular Biology
Studies on the P. aeruginosa T3S translocon assembly: interaction of PopD with membranes, Yuzhou Tang, Molecular and Cellular Biology
CANONICAL NOTCH SIGNALING POSITIVELY REGULATES MIR-155 TRANSCRIPTION IN A NFκB-DEPENDENT MANNER, Joe Torres, Molecular and Cellular Biology
CLPXP FUNCTIONS IN CAULOBACTER AS A UNIVERSAL AND SPECIES-SPECIFIC PROTEASE, Robert Vass, Molecular and Cellular Biology
CHARACTERIZATION OF SHE1 SPINDLE ROLE USING CEULLULAR, BIOCHEMICAL, AND BIOPHYSICAL METHODS, Yili Zhu, Molecular and Cellular Biology
Dissertations from 2017
Notch1 Modification and Signaling in T Helper Cell Differentiation, Karthik Chandiran, Molecular and Cellular Biology
Pore forming protein assembly and the use in nanopore sensing: a study on E. coli proteins ClyA and OmpG, Monifa Fahie, Molecular and Cellular Biology
Adaptors at Work: Regulation of Bacterial Proteolysis by Adaptor Hierarchies, Kamal Joshi, Molecular and Cellular Biology
THE KEY QUESTION IN SYMBIOTIC NITROGEN FIXATION: HOW DOES HOST MAINTAIN A BACTERIAL SYMBIONT?, Onur Oztas, Molecular and Cellular Biology
Dissecting Molecular Pathways that ensure Proper Chromosome Segregation and Cell Division, Anna Ye, Molecular and Cellular Biology
Dissertations from 2016
The Role of NOTCH3 Signaling in T Helper Cell Differentiation and Induction of EAE, Furkan Ayaz, Molecular and Cellular Biology
Studies of Kinetochore Mechanobiology in Drosophila, Stuart Cane, Molecular and Cellular Biology
Investigating the impact of small molecule ligands and the proteostasis network on protein folding inside the cell, Karan Hingorani, Molecular and Cellular Biology
The Cellular Context of Estradiol Regulation in the Zebra Finch Auditory Forebrain, Maaya Ikeda, Molecular and Cellular Biology
Exploring the Impact of the E. coli Proteostasis Network on the Folding Fate of Proteins with Different Intrinsic Biophysical Properties, Kristine Faye R. Pobre, Molecular and Cellular Biology
DNA-Based Epigenetic Changes in Recurrent and Tamoxifen-Resistant Breast Cancer, Kristin E. Williams, Molecular and Cellular Biology
Alternative Methods for the Treatment of Chemo-Resistant Cancers, Kaitlyn Wong, Molecular and Cellular Biology
Inhibition of DNA Methylation in Acquired Tamoxifen-Resistant Breast Cancer: Cell Line Model and Clinical Implications, Stephanie Zimmers, Molecular and Cellular Biology
Dissertations from 2015
Uncovering New Roles for the Cell Surface Protease ADAM13 in Neural Crest Migration, Genevieve Abbruzzese, Molecular and Cellular Biology
Biophysical Characterization of Katanin’s Regulation of Microtubules, Megan E. Bailey, Molecular and Cellular Biology
How to Build a Spinal Cord: Exploring Radial Glial Proliferation and their Contribution to Embryonic Neurogenesis, Kimberly A. Johnson, Molecular and Cellular Biology
NEW INSIGHTS INTO THE ROLE OF THE UDP-GLUCOSE: GLYCOPROTEIN GLUCOSYLTRANSFERASE 1 IN THE ENDOPLASMIC RETICULUM QUALITY CONTROL, Abla Tannous, Molecular and Cellular Biology
Dissertations from 2014
THE ESTRADIOL-INDUCED TRANSCRIPTOME OF THE FEMALE MOUSE ANTEROVENTRAL PERIVENTRICULAR NUCLEUS: MORE THAN JUST A KISS, Leah K. Aggison, Molecular and Cellular Biology
CHARACTERIZATION OF Ca2+ INFLUX PATHWAY(S) DURING MOUSE OOCYTE MATURATION, Banyoon Cheon, Molecular and Cellular Biology
Biophysical Studies of Axonal Transport, Leslie Cyle Conway, Molecular and Cellular Biology
NON-CANONICAL NOTCH SIGNALING REGULATES ACTIVATION AND DIFFERENTIATION OF PERIPHERAL CD4+ T CELLS, Anushka Dongre, Molecular and Cellular Biology
Engineering Probes to Detect Cholesterol Accessibility on Membranes Using Perfringolysin O, Benjamin B. Johnson, Molecular and Cellular Biology
MASS SPECTROMETRY BASED EXPERIMENTAL STRATEGIES TO CHARACTERIZE NATIVE AND NON-NATIVE DISULFIDE BONDS IN CYSTEINE-RICH PROTEIN THERAPEUTICS, Adriana Z. Kita, Molecular and Cellular Biology
STRUCTURAL BIOLOGY AND PHARMACOLOGY OF HUMAN CATHEPSIN A AND NEURAMINIDASE 1, Nilima Kolli, Molecular and Cellular Biology
NOVEL STRATEGIES TO MODULATE SYNAPTIC COMMUNICATION AND INVESTIGATE THE ROLE OF HDAC6 IN ALZHEIMER’S DISEASE, Kathryne A. Medeiros, Molecular and Cellular Biology
THE IDENTIFICATION AND CHARACTERIZATION OF A GROUP OF ER TPR-CONTAINING ADAPTER PROTEINS, johan C. Sunryd, Molecular and Cellular Biology
Dissertations from 2013
Regulation and Action of Skp2 and Rhoa in Cell and Tumor Models: Investigation into the Molecular Mechanisms Responsible for the Aggressive Phenotype of Triplenegative Breast Cancer, Katrina D. Fagan-Solis, Molecular and Cellular Biology
The Unavoidable Threat of Aggregation: Implications for Folding and Function of a β-Rich Protein, Mylene Hazelle Anne Ferrolino, Molecular and Cellular Biology
The Role of YKL-40 in the Progression of Glioblastoma, Ralph Anthony Francescone, Molecular and Cellular Biology
WC1 Functions as a Co-Receptor and A Pattern Recognition Receptor In Bovine Gamma delta T Cells, Hao-Ting Hsu, Molecular and Cellular Biology