Dissertations from 2013
Regulation and Action of Skp2 and Rhoa in Cell and Tumor Models: Investigation into the Molecular Mechanisms Responsible for the Aggressive Phenotype of Triplenegative Breast Cancer, Katrina D. Fagan-Solis
Dissertations from 2012
Structure, function, and pharmacological chaperoning of human alpha-N-acetylgalactosaminidase, Nathaniel E Clark
Molecular Interactions of the Tick Salivary Protein Salp15, Cassidy Dobson
Identification and Functional Characterization of the Zebrafish Gene Quetschkommode (que), Timo Friedrich
Individual polychlorinated biphenyl (PCB) congeners interact to disrupt thyroid hormone action during development, Stefanie Giera
The viroporin activity of VP2, VP3 and VP4 contribute to the SV40 viral life cycle, Kristina M Giorda
Target Recognition and Competitive Synaptogenesis in the Drosophila Giant Fiber System, Jason Joseph Hill
Runx1 regulates c-Myc expression and the expansion of hematopoietic precursors in a C-terminally dependent manner, Paejonette Jacobs
Structural studies of membrane-assembled PopD and PopB, the Pseudomonas aeruginosa type 3 secretion translocators, Fabian B Romano Chernac
Molecular and Cellular Mechanisms of Dopamine Signaling in C. elegans, Khursheed Ahmad Wani
Dissertations from 2011
The Role of Bacteriocins in Mediating Interactions of Bacterial Isolates from Cystic Fibrosis Patients, Emine Suphan Bakkal
Mitochondrial DNA Polymerase IB: Functional Characterization of a Putative Drug Target for African Sleeping Sickness, David F. Bruhn
The Role of the SUPRMAM1 Locus in Responses to Ionizing Radiation and Susceptibility to Mammary Tumors, Nicholas B. Griner
Xenopus ADAM13 and ADAM19 are Important for Proper Convergence and Extension of the Notochord, Russell David Neuner
Probing the regulation of vasculogenic mimicry in glioblastoma: Implications for treatment in patients, Stephen J. Scully
Components of a Protein Machine: Allosteric Domain Assembly and a Disordered C-terminus Enable the Chaperone Functions of Hsp70, Robert G. Smock
Regulation of mammary stem/progenitor cells by p53 and parity, Luwei Tao
Functional tests of structural models for abortive cycling in T7 RNA polymerase, Ankit V Vahia
Dissertations from 2010
An integrative approach towards understanding the structure-function relationship of the epigenetic regulator methyl CpG binding protein 2, Rajarshi P Ghosh
The Role of Runx1 N-Terminal Splice Isoforms in Hematopoietic Development, Emmett E. Hedblom
Beyond cell Adhesion: Exploring the Role of Cadherin-11 Extracellular Processing by ADAM Metalloproteases in Cranial Neural Crest Migration, Catherine D. McCusker
Notch 1 Mediated Inhibition of Nur77-induced apoptosis: Implications for T-cell Leukemia, Jonathan George Rud
New Insights in the TSSK Family: Studies in the Activity and Function of the Testis Specific Serine Kinases, Julian Sosnik
Dissertations from 2009
The Parkin-like ubiquitin E3 ligase Ariadne-1 in the mammalian brain: Potential implications for neurodegenerative disease, Juan G Cadena
The active site chemistry of factor inhibiting HIF-1, coordination, bonding, and reaction, Yuan-Han Chen
The role of EDEM1 in the quality control and degradation of misfolded glycoproteins, James H Cormier
Delayed Anesthetic Preconditioning and Metallothioneins I+II: Novel Mediators of Anesthetic-Induced Protection, Scott David Edmands
The Activity of eg5 and Dynein During Mammalian Mitosis, Nicholas P. Ferenz
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome, Mona Gupta
The Conformational Gymnastics of the Escherichia Coli SecA Molecular Machine and its Interactions with Signal Sequences, Jenny Lynn Maki
The role of the ER glucosyltransferase in the quality control of glycoprotein maturation, Bradley R Pearse
The role of ERalpha, ERbeta and phytoestrogens from soy in p53-mediated response to DNA damage in mammary epithelium, Erick Roman Perez
Determinants for Stop-Transfer and Post-Import Pathways for Protein Targeting to the Chloroplast Inner Envelope Membrane, Antonio Americo Barbosa Viana
Dissertations from 2008
Regulation of RecA-dependent homologous recombination by 3'-5' exonucleases and the UvrD helicase in Escherichia coli K-12, Richard C Centore
Regulation of Notch signaling by the E3 ubiquitin ligase Cbl-b and its role in CD4+ T cell anergy, Ameya S Champhekar
Functional analysis of Moe (Epb4.1l5) in zebrafish development and the identification of novel Epb4.1l5 binding proteins, Arne K Christensen
The role of ovarian hormones in p53-mediated resistance to mammary tumorigenesis, Karen A Dunphy
Drivers performance in response to sight-limited and multi-threat crash scenarios at mid-block crosswalks: An evaluation of advance yield markings and sign prompts, Lisandra Garay-Vega
The roles of signal peptide peptidase-like proteases in Arabidopsis thaliana, Sungwon Han
A post-import pathway for protein targeting to chloroplast inner membrane, Ming Li
Hormones, growth factors, and the regulation of tumor suppressor pathways involved in parity-induced protection of breast cancer, Lesley Anne Mathews
Novel developmental functions of the Drosophila SOX gene Dichaete, Krishna V Melnattur
Organization and maintenance of the motor nerve terminal: Roles for presynaptic actin and perisynaptic Schwann cells, Stephanie Anne Moeckel Cole
Organization and dynamics of actin and myosin during cytokinesis in mammalian epithelial cells, Kausalya Murthy
The ubiquitin E3 ligase Human Homolog of Drosophila Ariadne-1 (HHARI) is a structural and functional homolog of Parkin and is required for myogenesis, Sangram S Parelkar
Genetic studies of the regulation of RecA activity in Escherichia coli: A two filament model, Nicholas Renzette
Environmental toxicants and white matter composition: Understanding the role of thyroid disruption, David S Sharlin
Characterization of bendless and interacting partners in Drosophila central synapse formation, Smitha Babu Uthaman
The role of GTP regulation in chloroplast import, Fei Wang
Dissertations from 2007
Energy availability signals and the prohormone convertase 1 gene are regulated by Nhlh2, Dana L Fox
Targeting bacteriolytic therapy of solid tumors with attenuated Salmonella typhimurium, Sabha Ganai
Notch functions from the cytoplasm to the nucleus during T cell activation, Hyun Mu Shin
Contribution of non-centrosomal microtubules to mitotic spindle assembly in mammalian cells, Ustun Serdar Tulu
Modulation of Nhlh2 expression by energy availability leads to downstream effects on body weight regulation, Kristen R Vella
Investigations of glycoprotein co-translational maturation in the cell, Ning Wang
Dissertations from 2006
Functional analysis of Hic-5/ARA55 isoforms in C2C12 myogenesis, Zhengliang Gao
The effects of polychlorinated biphenyls on thyroid hormone-mediated action in vivo and in vitro, Kelly J Gauger
Regulation of p53 by Mdm4 and ovarian hormones in mouse mammary glands, Shaolei Lu
Postsynaptic mechanisms during synaptic plasticity at the Drosophila neuromuscular junction, Dennis Mathew
The influence of WC1 isoforms on gammadelta T cell function, Aric N Rogers
Dissertations from 2005
The impact of PCBs on thyroid hormone directed brain development in rats, Eric A Iannacone
Molecular and functional analysis of mutations that result in insecticide resistance in Colorado potato beetle, Hyo Jeong Kim
Microtubule dynamics and behavior during the assembly and disassembly of mammalian mitotic spindles, Nasser M Rusan
Multiple roles for hedgehog signaling in zebrafish pituitary development, Jennifer L Sbrogna
Cloning and functional characterization of the zebrafish mutation belladonna, Anandita Seth
The action of T- and CS-syndrome pyrethroids on voltage-sensitive calcium channels in rat brain, Steven B Symington
Receptor clusters and dynamics in kinase regulation in bacterial chemotaxis, Li Zhi
Dissertations from 2004
Estrogen and progesterone regulate p53 activity in the mouse mammary epithelium through transforming growth factor beta dependent pathways, Klaus A Becker
Notch-1 regulates IFN-gamma secretion through activation of NF-kappaB, Sridevi Gottipati
NIH 3T3 fibroblast adhesion to a fibronectin substrate: The role of the arachidonic acid signaling pathway, Joffre Angelo Green
The role of Notch in T cell activation and development, Amy Marie Laws
Dietary phenolics for chemoprevention, Patrick P McCue
Understanding the allosteric mechanism of the Escherichia coli Hsp70 molecular chaperone, DnaK, Renuka Sivendran
Using the mouse egg as a model system for the study of intracellular calcium signaling mechanisms, Jeremy T Smyth
Dissertations from 2003
Cyclooxygenase and cyclic AMP-dependent protein kinase regulate actin organization and cell motility, Honor L Glenn
Characterization and analysis of the cuticlin gene family of the human parasite Onchocerca volvulus, Michelle Renee Lizotte-Waniewski
The role of N-linked glycans in protein quality control in the early secretory pathway, Sherri L Svedine
When stress is good: Exercise and stress protein responses in mice and humans, Heather Sue Thompson
The role of oxidative stress in apoptosis, Noriko Tonomura
Overlapping and distinct functions for Gli proteins: Key mediators of hedgehog signaling in cell specification during embryonic development, Oksana V Tyurina
Acheron, a novel regulator of myoblast differentiation, Zhaohui Wang