Theses from 2024
The Impact of a Non-ionic Adjuvant to the Persistence of Pesticides on Produce Surfaces, Daniel Barnes, Molecular & Cellular Biology
Investigating the Role of Got2 in Murine Organogenesis and Placenta Development, Olivia Macrorie, Molecular & Cellular Biology
Chromatin Accessibility Impacts Knockout of Mt-Bell4 Transcription Factor, Thomas Redden, Molecular & Cellular Biology
UNDERSTANDING THE FUNCTIONAL IMPACT OF DISEASE-ASSOCIATED PHOSPHORYLATION SITES ON THE NEURODEGENERATIVE PROTEIN TAU, Navya T. Sebastian, Molecular & Cellular Biology
Theses from 2023
Elucidating the Priming Mechanism of ClpXP Protease by Single-Domain Response Regulator CpdR in Caulobacter crescentus, Kimberly E. Barker, Molecular & Cellular Biology
The Discovery of a Novel Bacteria from a Large Co-assembly of Metagenomes, Matthew Finkelberg, Molecular & Cellular Biology
Investigating Diterpene Biosynthesis in Medicago Truncatula, Sungwoo Hwang, Molecular & Cellular Biology
Combining Simulation and the MspA Nanopore to Study p53 Dynamics and Interactions, Samantha A. Schultz, Molecular & Cellular Biology
Caulobacter ClpXP Adaptor PopA’s Domain Interactions in the Adaptor Hierarchy of CtrA Degradation, Thomas P. Scudder, Molecular & Cellular Biology
Climate Change, Giant Viruses and Their Putative Hosts, Sarah K. Tucker, Molecular & Cellular Biology
Theses from 2022
Changes in Gene Expression From Long-Term Warming Revealed Using Metatranscriptome Mapping to FAC-Sorted Bacteria, Christopher A. Colvin, Molecular & Cellular Biology
Determining CaMKII Variant Activities and Their Roles in Human Disease, Matthew J. Dunn, Molecular & Cellular Biology
Developmental Exposures to PFAS Mixtures Impair Elongation of the Exocrine Pancreas in Zebrafish (Danio rerio), Emily M. Formato, Molecular & Cellular Biology
A Metatranscriptomic Analysis of the Long-Term Effects of Warming on the Harvard Forest Soil Microbiome, Brooke A. Linnehan, Molecular & Cellular Biology
Characterization of the Poly (ADP-Ribose) Polymerase Family in the Fusarium oxysporum Species Complex, Daniel Norment, Molecular & Cellular Biology
Theses from 2021
Exploring Knockdown Phenotypes and Interactions between ATAD3 Proteins in Arabidopsis thaliana, Eli S. Gordon, Molecular & Cellular Biology
Development of a Site-Specific Labeling Assay to Study the Pseudomonas aeruginosa Type III Secretion Translocon in Native Membranes, Kyle A. Mahan, Molecular & Cellular Biology
Liposomal Nanoparticles Target TLR7/8-SHP2 to Repolarize Macrophages to Aid in Cancer Immunotherapy, Vaishali Malik, Molecular & Cellular Biology
Hsp70 Phosphorylation: A Case Study of Serine Residues 385 and 400, Sashrika Saini, Molecular & Cellular Biology
Activation of Nrf2 at Critical Windows of Development Alters Protein S-Glutathionylation in the Zebrafish Embryo (Danio rerio), Emily G. Severance, Molecular & Cellular Biology
Utilizing Fluorescence Microscopy to Characterize the Subcellular Distribution of the Novel Protein Acheron, Varun Sheel, Molecular & Cellular Biology
Theses from 2020
The Association Between Sperm DNA Methylation and Sperm Mitochondrial DNA Copy Number, Emily Houle, Molecular & Cellular Biology
Gene Expression Regulation in the Mouse Liver by Mechanistic Target Of Rapamycin Complexes I and II, Anthony Poluyanoff, Molecular & Cellular Biology
Sperm Mitochondrial DNA Biomarkers as a Measure of Male Fecundity and Overall Sperm Quality, Allyson Rosati, Molecular & Cellular Biology
Exploration of the Association between Muscle Volume and Bone Geometry Reveals Surprising Relationship at the Genetic Level, Prakrit Subba, Molecular & Cellular Biology
Theses from 2019
Studies on the Interaction and Organization of Bacterial Proteins on Membranes, Mariana Brena, Molecular & Cellular Biology
Investigating The Role Of LBH During Early Embryonic Development In Xenopus Laevis, Emma Weir, Molecular & Cellular Biology
Theses from 2018
Exploring the Influence of PKC-theta Phosphorylation on Notch1 Activation and T Helper Cell Differentiation, Grace Trombley, Molecular & Cellular Biology
Theses from 2017
Partial Craniofacial Cartilage Rescue in ace/fgf8 Mutants from Compensatory Signaling From the Ventricle of Danio Rerio, Douglas A. Calenda II, Molecular & Cellular Biology
THE FAR C-TERMINUS OF TPX2 CONTRIBUTES TO SPINDLE MORPHOGENESIS, Brett Estes, Molecular & Cellular Biology
Characterization of Calcium Homeostasis Parameters in TRPV3 and CaV3.2 Double Null Mice, Aujan Mehregan, Molecular & Cellular Biology
Microtransplantation of Rat Brain Neurolemma into Xenopus Laevis Oocytes to Study the Effect of Environmental Toxicants on Endogenous Voltage-Sensitive Ion Channels, Edwin Murenzi, Molecular & Cellular Biology
Regulation of Katanin Activity on Microtubules, Madison A. Tyler, Molecular & Cellular Biology
Theses from 2016
The Role of MicroRNAs in Regulating the Translatability and Stability of Target Messenger RNAs During the Atrophy and Programmed Cell Death of the Intersegmental Muscles of the Tobacco Hawkmoth Manduca sexta., Elizabeth Chan, Molecular & Cellular Biology
An in Vivo Study of Cortical Dynein Dynamics and its Contribution to Microtubule Sliding in the Midzone, Heather M. Jordan, Molecular & Cellular Biology
A Genetic Analysis of Cichlid Scale Morphology, Kenta C. Kawasaki, Molecular & Cellular Biology
Modulation of Notch in an Animal Model of Multiple Sclerosis, Manit Nikhil Munshi, Molecular & Cellular Biology
One-Carbon Metabolism Related B-Vitamins Alter The Expression Of MicroRNAS And Target Genes Within The Wnt Signaling Pathway In Mouse Colonic Epithelium, Riccardo Racicot, Molecular & Cellular Biology
Characterizing the Inhibition of Katanin Using Tubulin Carboxy-Terminal Tail Constructs, Corey E. Reed, Molecular & Cellular Biology
The Identification of Notch1 Functional Domains Responsible for its Physical Interaction with PKCθ, Wesley D. Rossiter, Molecular & Cellular Biology
Dynamics of Microtubule Networks with Antiparallel Crosslinkers, Kasimira T. Stanhope, Molecular & Cellular Biology
Modifications of Myofilament Structure and Function During Global Myocardial Ischemia, Mike K. Woodward, Molecular & Cellular Biology
Theses from 2015
Regulation of Jak1 and Jak2 Synthesis through Non-Classical Progestin Receptors, Hillary Adams, Molecular & Cellular Biology
Antineoplastic Effects of Rhodiola Crenulata on B16-F10 Melanoma, Maxine Dudek, Molecular & Cellular Biology
RNAi Validation of Resistance Genes and Their Interactions in the Highly DDT-Resistant 91-R Strain of Drosophila Melanogaster, Kyle Gellatly, Molecular & Cellular Biology
Characterization of Protein-Protein Interactions for Therapeutic Drug Design Utilizing Mass Spectrometry, Alex J. Johnson, Molecular & Cellular Biology
Promoting Extracellular Matrix Crosslinking in Synthetic Hydrogels, Marcos M. Manganare, Molecular & Cellular Biology
Characterization of the Reconstituted and Native Pseudomonas aeruginosa Type III Secretion System Translocon, Kathryn R. Monopoli, Molecular & Cellular Biology
Thermocycle-regulated WALL REGULATOR INTERACTING bHLH Encodes a Protein That Interacts with Secondary-Cell-Wall-Associated Transcription Factors, Ian P. Whitney, Molecular & Cellular Biology
Theses from 2014
Engineering Camelina sativa for Biofuel Production via increasing oil yield and tolerance to abiotic stresses, Kenny Ablordeppey, Molecular & Cellular Biology
Designing a Pore-Forming Toxin Cytolysin A (ClyA) Specific to Target Cancer Cells, Alzira Rocheteau Avelino, Molecular & Cellular Biology
The Role of the Novel Lupus Antigen, Acheron, in Moderating Life and Death Decisions, Ankur Sheel, Molecular & Cellular Biology
Expression and Purification of Human Lysosomal β-galactosidase from Pichia Pastoris, Sarah E. Tarullo, Molecular & Cellular Biology
Properties of Potential Substrates of a Cyanobacterial Small Heat Shock Protein, Yichen Zhang, Molecular & Cellular Biology
Theses from 2013
Characterizing the Heavy Metal Chelator, Tpen, as a Ca2+ Tool in the Mammalian Oocyte, Robert A. Agreda Mccaughin, Molecular & Cellular Biology
Sustainable Biofuels Production Through Understanding Fundamental Bacterial Pathways Involved in Biomass Degradation and Sugar Utilization, James CM Hayes, Molecular & Cellular Biology
Stiffness and Modulus and Independent Controllers of Breast Cancer Metastasis, Dannielle Ryman, Molecular & Cellular Biology
Theses from 2012
The Pyrethroid Deltamethrin, Which Causes Choreoathetosis with Salivation (CS-Syndrome), Enhances Calcium Ion Influx via Phosphorylated CaV2.2 expresssed in Xenopus laevis oocytes, Anna-maria Alves, Molecular & Cellular Biology
A Test of the Hypothesis That Environmental Chemicals Interfere With Thyroid Hormone Action in Human Placenta, Katherine Geromini, Molecular & Cellular Biology
Analyzing the Role of Reactive Oxygen Species in Male-Female Interactions in Arabidopsis thaliana., Eric A. Johnson, Molecular & Cellular Biology
Rhythmic Growth And Vascular Development In Brachypodium Distachyon, Dominick A. Matos, Molecular & Cellular Biology
Polymer Prodrug Conjugation to Tumor Homing Mesenchymal Stem Cells, Nick Panzarino, Molecular & Cellular Biology
Investigation of Differential Vector Competence of Bartonella quintana in Human Head and Body Lice, Domenic j. Previte, Molecular & Cellular Biology
Downregulation of Cinnamyl Alcohol Dehydrogenase or Caffeic Acid O-Methyltransferase Leads to Improved Biological Conversion Efficiency in Brachypodium distachyon, Gina M. Trabucco, Molecular & Cellular Biology
Theses from 2011
Evolutionary Relationship of the ampC Resistance Gene In E. cloacae, Shanika S. Collins, Molecular & Cellular Biology
Sex Difference in Calbindin Cell Number in the Mouse Preoptic Area: Effects of Neonatal Estradiol and Bax Gene Deletion, Richard F. Gilmore III, Molecular & Cellular Biology
In Vivo Investigations of Polymer Conjugates as Therapeutics, Elizabeth M. Henchey, Molecular & Cellular Biology
Examination of Sexually Dimorphic Cell Death in the Pubertal Mouse Brain, Amanda Holley, Molecular & Cellular Biology
Human Niemann-Pick Type C2 Disease Protein Expression, Purification and Crystallization, Yurie T. Kim, Molecular & Cellular Biology
Revealing the Localization of the Class I Formin Family in the Moss Physcomitrella patens Using Gene Targeting Strategies, Kelli Pattavina, Molecular & Cellular Biology
Connecting Motors and Membranes: A Quantitative Investigation of Dynein Pathway Components and in vitro Characterization of the Num1 Coiled Coil Domain, Bryan J. St. Germain, Molecular & Cellular Biology
Theses from 2010
The Protective Effects A Full-term Pregnancy Plays Against Mammary Carcinoma, Matthew p. Carter, Molecular & Cellular Biology
Analysis Of An Actin Binding Guanine Exchange Factor, Gef8, And Actin Depolymerizing Factor In Arabidopsis Thaliana., Aleksey Chudnovskiy, Molecular & Cellular Biology
The Role of Ykl-40, a Secreted Heparin-Binding Glycoprotein, in Tumor Angiogenesis, Metastasis, and Progression: a Potential Therapeutic Target, Michael Faibish, Molecular & Cellular Biology
In Vivo Visualization of Hedgehog Signaling in Zebrafish, Christopher J. Ferreira, Molecular & Cellular Biology
An In Vivo Study of the Mammalian Mitotic Kinesin Eg5, Alyssa D. Gable, Molecular & Cellular Biology
Identification of Dynein Binding Sites in Budding Yeast Pac1/LIS1, Christopher W. Meaden, Molecular & Cellular Biology
Functional Characterization of Arabidopsis Formin Homologues Afh1, Afh5, Afh6, Afh7 and Afh8, Shahriar Niroomand, Molecular & Cellular Biology
Regulation of Crbp1 In Mammary Epithelial Cells, Stacy L. Pease, Molecular & Cellular Biology
In Vivo Labeling Of A Model β-Clam Protein With A Fluorescent Amino Acid, Mangayarkarasi Periasamy, Molecular & Cellular Biology
In Vivo Characterization of Interactions Among Dynein Complex Components at Microtubule Plus Ends, Karen M. Plevock, Molecular & Cellular Biology
Anti-Diabetic Potentials of Phenolic Enriched Chilean Potato and Select Herbs of Apiaceae and Lamiaceae Families, Fahad Saleem, Molecular & Cellular Biology
Interconversion of the Specificities of Human Lysosomal Enzymes, Ivan B. Tomasic, Molecular & Cellular Biology
Deletions of Fstl3 and/or Fst Isoforms 303 and 315 Results in Hepatic Steatosis, Nathan A. Ungerleider, Molecular & Cellular Biology
Theses from 2009
A New Laser Pointer Driven Optical Microheater for Precise Local Heat Shock, Mike Placinta, Molecular & Cellular Biology
Theses from 2008
Cysteine Dioxygenase: The Importance of Key Residues and Insight into the Mechanism of the Metal Center, Jonathan H. Leung, Molecular & Cellular Biology
Invertebrate Phenology and Prey Selection of Three Sympatric Species of Salmonids; Implications for Individual Fish Growth, Jeffrey V. Ojala, Wildlife & Fisheries Conservation
Paralemmin Splice Variants and mRNA and Protein Expression in Breast Cancer, Casey M. Turk, Molecular & Cellular Biology
Stability of the frog motor nerve terminal: roles of perisynaptic Schwann cells and muscle fibers, Ling Xin, Molecular & Cellular Biology
Theses from 2007
Antioxidant Response Mechanism in Apples during Post-Harvest Storage and Implications for Human Health Benefits, Ishan Adyanthaya, Molecular & Cellular Biology
Progress Towards A Model Flavoenzyme System, Kevin M. Bardon, Molecular & Cellular Biology
The effect of Rhodiola crenulata on a highly metastatic murine mammary carcinoma, Jessica L. Doerner, Molecular & Cellular Biology