Publication Date
2016
Journal or Book Title
WIREs Nanomedicine and Nanobiotechnology
Abstract
There has been increasing interest in complex coacervates for deriving and trans- porting biomaterials. Complex coacervates are a dense, polyelectrolyte-rich liq- uid that results from the electrostatic complexation of oppositely charged macroions. Coacervates have long been used as a strategy for encapsulation, par- ticularly in food and personal care products. More recent efforts have focused on the utility of this class of materials for the encapsulation of small molecules, pro- teins, RNA, DNA, and other biomaterials for applications ranging from sensing to biomedicine. Furthermore, coacervate-related materials have found utility in other areas of biomedicine, including cartilage mimics, tissue culture scaffolds, and adhesives for wet, biological environments. Here, we discuss the self- assembly of complex coacervate-based materials, current challenges in the intel- ligent design of these materials, and their utility applications in the broad field of biomedicine.
DOI
https://doi.org/10.1002/wnan.1442
Recommended Citation
Perry, Sarah L. and Blocher, Whitney C., "Complex Coacervate-based Materials for Biomedicine" (2016). WIREs Nanomedicine and Nanobiotechnology. 835.
https://doi.org/10.1002/wnan.1442
Included in
Chemical Engineering Commons, Nanomedicine Commons, Nanoscience and Nanotechnology Commons
Comments
Blocher, W. C. and Perry, S. L. (2016), Complex coacervate-based materials for biomedicine. WIREs Nanomed Nanobiotechnol. doi:10.1002/wnan.1442