Journal or Book Title
Drug Discovery Today
Metastasis, drug resistance and recurrence in cancer are regulated by the tumor microenvironment. This review describes recent advances in understanding how cancel cells respond to extracellular environmental cues via integrins, how to build engineered microenvironments to study these interactions in vitro and how nanomaterials can be used to detect and target tumor microenvironments.
UMass Amherst Open Access Policy
Yoshii, Tatsuyuki; Geng, Yingying; Peyton, Shelly; Mercurio, Arthur M.; and Rotello, Vincent M., "Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine" (2016). Drug Discovery Today. 896.