Approximately one in nine babies born in the United States is premature and has low birthweight (LBW) with the second highest rates among Puerto Rican women (14.5%) (2). Disparities exist by socioeconomic status as well as by race and ethnicity. However, established risk factors only account for a portion of the disparities in adverse outcomes. Other factors that have not been studied as frequently include environmental, contextual, and neighborhood-level factors. These are of particular interest because of their potentially modifiable nature. We evaluated the association between neighborhood poverty, overall neighborhood crime, and violent neighborhood crime and adverse birth outcomes using data from Proyecto Buena Salud, a prospective cohort study of 1,610 Hispanic women conducted from 2006-10. Participant addresses were mapped and census block-level crime information from 2006-2010 using AGS CrimeRisk data to model the association between neighborhood crime and preterm birth, LBW, and small-for-gestational age (SGA) adjusting for individual demographic, medical, and socioeconomic variables. We found no association between neighborhood poverty and preterm birth or LBW. There was a positive association between neighborhood poverty and SGA (OR 2.0, 95% CI 1.114-3.585) when comparing women who lived in the highest quartile of neighborhood poverty to women who lived in the lowest quartile for neighborhood poverty when adjusted for age of the mother, pre-pregnancy BMI, and stress in the second and third trimesters. There was no association between overall neighborhood crime and adverse birth outcomes. There was no association between violent neighborhood crime and preterm birth or LBW. Violent neighborhood crime was positively associated with a 1.5 times higher odds SGA (95% CI: 1.03-2.2) when adjusted for smoking before pregnancy, smoking during early pregnancy, education levels, parity, age of the mother, pre-pregnancy BMI, and gestational weight gain. Women who lived in the highest quartile of violent neighborhood crime had 2.1 times higher odds of SGA (95% CI: 1.2-3.4, p-trend of 0.0037) compared to women who lived in the lowest quartile of violent neighborhood crime when adjusted for smoking before pregnancy, education levels, age of the mother, and pre-pregnancy BMI.