his study evaluates the performance of structural, chlorophyll-based, and photochemical indices to detect maize water status and to assess production based on five years of field experiments (2013–2017) during the primary growth stages. We employed three categories of indicators, including water condition and productive and thermal indicators, to quantify the responses of summer maize under continuous water stress from drought to waterlogging conditions. Furthermore, we adopted several spectral indices to assess their sensitivity to three categories of metrics. The results showed the association is the best between the treatment level and Leaf Water Content (LWC). The waterlogging treatment influenced Leaf Water Potential (LWP) in moderate drought stress. Severe drought stress caused the strongest reduction in productivity from both Leaf Area Index (LAI) and chlorophyll content. In terms of sensitivity of various indices, red-edge-position (REP) was sensitive to maize water conditions LWP, LAI and chlorophyll content. Photochemical Reflectance Index (PRI) and Normalized Difference Vegetation Index (NDVI) were the most and second most sensitive indices to productive indicators, respectively. The results also showed that no indices were capable of capturing the information of Crop Water Stress Index (CWSI).