Predicting the resource consumption in the built environment and its associated environmental consequences (urban metabolism analysis) is one of the core challenges facing policy-makers and planners seeking to increase the sustainability of urban areas. There is a critical need for a single integrated framework to analyze the consequences of urban growth and eventually predict the impacts of sustainable policies on the urbanscape. This dissertation presents the development of an Integrated Urban Metabolism Analysis Tool (IUMAT) – an analytical framework that simulates urban metabolism by integrating urban subsystems in a single comprehensive computational environment. It reviews the existing literature on urban sustainability, urban metabolism, as well as introducing the general framework for IUMAT. IUMAT uses three separate models for quantifying environmental impacts of land-use transition, consumption of resources, and transportation. This work outlines the development of IUMAT Land-Use Model that uses Remote Sensing, GIS, and Artificial Neural Networks (ANNs) to predict land use change patterns. By using Density-Based Spatial Clustering and normal equations, this dissertation introduces a method for generating building-form variables from Light Detection and Ranging (LIDAR) data, which can be used as a new determinant factor in land-use change modeling. The proposed Land-use Model, within IUMAT or other analytical models, can be useful to local planning officials in understanding the complexity of land-use change and developing enhanced land-use policies.