We have observed the 110-101 pure rotational transitions of both H216O and H218O toward Sagittarius B2 using the Submillimeter Wave Astronomy Satellite. The spectra thereby obtained show a complex pattern of absorption and—in the case of H216O—emission, with numerous features covering a wide range of LSR velocities (-130 to 130 km s-1) and representing absorption both in gas associated with Sgr B2 as well as by several components of foreground gas along the line of sight. The ortho-water abundance derived for the absorbing foreground gas is ~6 × 10-7 relative to H2.