This study investigates the potential role of local governments in assisting Small Quantity Generators (SQGs) of hazardous waste to comply with federal and state regulations. A survey of state regulatory agencies in the Northeast Region revealed that only a limited number of states effectively utilize local governments in this capacity, with most rating their involvement as somewhat effective or minimal. The research also explores the challenges faced by SQGs and regulatory agencies, highlighting barriers such as SQGs’ reluctance to disclose hazardous waste practices and the limited effectiveness of state agencies in providing support. The study emphasizes the need for locally administered, sensitive programs that combine personal communication and technical expertise to help SQGs address waste management without fear of punitive consequences. Recommendations include developing cooperative programs involving local governments, Cooperative Extension Services, Chambers of Commerce, and trade associations to foster compliance through support rather than enforcement.