Many existing machine learning (ML) algorithms cannot be viewed as gradient descent on some single objective. The solution trajectories taken by these algorithms naturally exhibit rotation, sometimes forming cycles, a behavior that is not expected with (full-batch) gradient descent. However, these algorithms can be viewed more generally as solving for the equilibrium of a game with possibly multiple competing objectives. Moreover, some recent ML models, specifically generative adversarial networks (GANs) and its variants, are now explicitly formulated as equilibrium problems. Equilibrium problems present challenges beyond those encountered in optimization such as limit-cycles and chaotic attractors and are able to abstract away some of the difficulties encountered when training models like GANs. In this thesis, I aim to advance our understanding of equilibrium problems so as to improve state-of-the-art in GANs and related domains. In the following chapters, I will present work on designing a no-regret framework for solving monotone equilibrium problems in online or streaming settings (with applications to Reinforcement Learning), ensuring convergence when training a GAN to fit a normal distribution to data by Crossing-the-Curl, improving state-of-the-art image generation with techniques derived from theory, and borrowing tools from dynamical systems theory for analyzing the complex dynamics of GAN training.