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Coffee and Tea Consumption and the Risk of Lung Cancer in a Population of Postmenopausal Women

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Abstract
Lung cancer has been the leading cause of cancer death in women for the past three decades. Although smoking is the most important risk factor for lung cancer, not all lung cancer deaths in American women are attributed to smoking and the role of dietary exposures remain unclear.In particular, the effect of coffee consumption and tea consumption on lung cancer risk remains inconclusive. Therefore we assessed these associations prospectively in 83,777 women between the ages of 50-79 who did not have a previous history of cancer. Daily coffee and tea consumption (cups/d) were assessed via a baseline questionnaire while the 1,038 lung cancer cases included in analysis were self-reported and verified by outcome assessors. Cox proportional hazard models, adjusted for important lung cancer risk factors, were used to model the associations. 71% of women reported drinking coffee daily while only 26% of participants drank tea. Preliminary results suggested a significant increase in lung cancer risk for caffeinated (HR=1.47, 95% CI 1.21-1.79), decaffeinated (HR=1.56, 95% CI 1.17-2.07) and total coffee (HR= 1.58, 95% CI 1.29-1.93) when comparing those in the highest consumption categories to non-drinkers, but no significant results were observed in these consumption groups in an analysis conducted with only non-smokers. Daily tea consumption was significantly associated with a reduction of risk (HR= 0.82, 95% CI 0.71-0.96). Our data suggests that there is no association between coffee consumption and lung cancer risk or tea consumption and lung cancer risk.
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thesis
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2014-05
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