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Title
Impact of Animal Protein and Plant Protein on the Gut Microbiota and Metabolites of C57BL/6J Mice
ORCID
https://orcid.org/0009-0005-2097-4309
Access Type
Open Access Thesis
Document Type
thesis
Embargo Period
3-28-2023
Degree Program
Food Science
Degree Type
Master of Science (M.S.)
Year Degree Awarded
2023
Month Degree Awarded
May
Abstract
Plant-derived protein has gained popularity in recent years due to its health and environmental impact. Studies comparing the health benefits of animal and plant protein have mostly focused on soy as a plant protein representative due to its popularity. Demand for other protein sources such as peas and fava beans has been increasing; thus, the health impact of plant protein sources other than soy must be assessed. Evidence has shown that diet influences the gut microbiota and the metabolites in the body. Metabolites associated with amino acids are strong contributors to the metabolite distinction between dietary animal and plant foods. Certain gut bacteria are also known to be able to metabolize amino acids, thus influencing their survival in the gut. To discern the impact of plant and animal-based proteins, namely soy, pea, faba bean, beef, chicken, and pork, on the host gut microbiota as well as the metabolic profile, male C57BL/6J mice were fed with the proteins for 8 weeks. Results showed that each protein source influenced the gut microbiota and metabolic profile differently. However, these impacts were not caused by the amino acid profile alone. Other factors, such as myoglobin in meats and phenolic compounds in plant proteins, also play a role.
DOI
https://doi.org/10.7275/34547506
First Advisor
Hang Xiao
Second Advisor
Eric Decker
Third Advisor
Zhenhua Liu
Recommended Citation
Soetyono, Levina, "Impact of Animal Protein and Plant Protein on the Gut Microbiota and Metabolites of C57BL/6J Mice" (2023). Masters Theses. 1286.
https://doi.org/10.7275/34547506
https://scholarworks.umass.edu/masters_theses_2/1286