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Dissertations from 2022

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CHARACTERIZING THE MULTIFACETED ROLES OF THE PROTEASOMAL DEUBIQUITINASE UCH37 IN PROTEOSTASIS, Heather A. Bisbee, Molecular and Cellular Biology

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Synthesis and targeting of the bacterial cell wall, Alam García-Heredia, Molecular and Cellular Biology

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Genetic and Environmental Regulation of Plant Growth, Kirk J-M MacKinnon, Molecular and Cellular Biology

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Principles of AAA+ Proteases, Samar Mahmoud, Molecular and Cellular Biology

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CHEMICAL BIOLOGY APPROACHES FOR TRACKING AND MANIPULATION OF MACROPHAGE PHENOTYPES, Javier A. Mas Rosario, Molecular and Cellular Biology

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Exposure to Endocrine Disrupting Chemicals and the Effects on Inflammation and Mammary Tumor Progression, Stephanie Morin, Molecular and Cellular Biology

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STRUCTURAL STUDIES OF CaMKII ACTIVATION AND OLIGOMERIZATION, Can Özden, Molecular and Cellular Biology

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Human Saposin B Ligand Binding and Presentation to α-Galactosidase A, Thomas K. Sawyer, Molecular and Cellular Biology

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EXTRACELLULAR MATRIX STIFFNESS AS A CUE TO SHAPE PHENOTYPIC EVOLUTION OF TRIPLE NEGATIVE BREAST CANCER, Ning-Hsuan Tseng, Molecular and Cellular Biology

Dissertations from 2021

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Substrate selection in endoplasmic reticulum protein quality control, Ben Adams, Molecular and Cellular Biology

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MECHANISMS OF MITOTIC CHECKPOINT SILENCING BY THE DISORDERED KINETOCHORE PROTEIN SPC105, Margaux Audett, Molecular and Cellular Biology

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DISCOVERING MECHANISMS DRIVING ADAPTIVE EVOLUTION IN THE CROSS-KINGDOM FUNGAL PATHOGEN FUSARIUM OXYSPORUM, Dilay Hazal Ayhan, Molecular and Cellular Biology

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BIOCHEMICAL STUDIES OF FABRY DISEASE AND FUCOSIDOSIS, Cameron Butova, Molecular and Cellular Biology

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PHARMACOLOGICAL CHAPERONING OF HUMAN LYSOSOMAL NEURAMINIDASE 1, Di Chu, Molecular and Cellular Biology

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RAPID CELL PHENOTYPING USING ARRAY-BASED SENSORS: APPLICATIONS IN CANCER STEM CELL THERAPY AND HIGH-CONTENT SCREENING, Yingying Geng, Molecular and Cellular Biology

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Mechanistic Insights into Diverse Protease Adaptor Functions, NATHAN J. KUHLMANN, Molecular and Cellular Biology

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It Takes a Village to Build a Brain: Defining the Heterogenous Glial and Neural Crest Contributions to Zebrafish Forebrain Development and Neurogenesis, Jake Schnabl, Molecular and Cellular Biology

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Understanding how CaMKII holoenzyme dynamics facilities activation-triggered subunit exchange, Ana P. Torres-Ocampo, Molecular and Cellular Biology

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APPLYING GENOME-WIDE ASSOCIATION IN THE FUNGAL PATHOGEN ASPERGILLUS FUMIGATUS TO IDENTIFY THE GENETIC CONTRIBUTORS OF ANTIFUNGAL SENSITIVITY AND THERMOTOLERANCE, Shu Zhao, Molecular and Cellular Biology

Dissertations from 2020

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Exploring Signatures of Host-Microbial Coevolution Between Colonic Bifidobacterium Species and Host Dietary Carbohydrates, Korin Albert, Molecular and Cellular Biology

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Defining the let-7 microRNA-mediated molecular mechanisms regulating T cell differentiation, Constance C. Angelou, Molecular and Cellular Biology

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INTER-INDIVIDUAL VARIATION IN RESPONSE TO ESTROGEN AND IMPLICATIONS FOR BREAST CANCER RISK, Amye L. Black, Molecular and Cellular Biology

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TPR-CONTAINING PROTEINS CONTROL PROTEIN ORGANIZATION AND HOMEOSTASIS FOR THE ENDOPLASMIC RETICULUM, Jill Bradley-Graham, Molecular and Cellular Biology

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Dissecting regulatory mechanisms of quorum sensing pathways in Bacillus subtilis, Patrick Hill, Molecular and Cellular Biology

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Multivesicular Release in Hair Cell Ribbon Synapses in the Bullfrog Amphibian Papilla, Fuu-Jiun Hwang, Molecular and Cellular Biology

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ROLES OF RECN DNA REPAIR PROTEIN AND PRIA DNA HELICASE IN MAINTAINING GENOMIC INTEGRITY OF ESCHERICHIA COLI K-12, Anastasiia N. Klimova, Molecular and Cellular Biology

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Hedgehog Signaling (Hh/Gli) Regulates Neurogenesis in the Zebrafish Hypothalamus, Ira Male, Molecular and Cellular Biology

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A Rational Design Approach to Developing Second Generation Fabry Disease Treatments, Matthew Metcalf, Molecular and Cellular Biology

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Improved Molecular Diagnostics for Soil-Transmitted Helminths, Nils Pilotte, Molecular and Cellular Biology

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CHARACTERIZING ADAPTIVE NON-CODING CHANGES IN THE REGULATION OF HUMAN GENE EXPRESSION, Jason Pizzollo, Molecular and Cellular Biology

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REDOX SIGNALING IN THE ZEBRAFISH EMBRYO AND IMPLICATIONS FOR ENDOCRINE PANCREAS MORPHOGENESIS, Archit Rastogi, Molecular and Cellular Biology

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Liver Kinase B1 isoform expression as a regulator of T cell phenotypic stability, Heather Sherman, Molecular and Cellular Biology

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Engineering mesothelin-binding proteins as targeted cancer diagnostics and therapeutics, Allison Rita Sirois, Molecular and Cellular Biology

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ACCESSORY GENES CONTRIBUTE TO REWIRING THE TRANSCRIPTIONAL NETWORK IN FUSARIUM OXYSPORUM, He Yang, Molecular and Cellular Biology

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The Lon protease integrates protein quality control with DNA damage responses in Caulobacter crescentus, Rilee D. Zeinert, Molecular and Cellular Biology

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DE-CODING THE IMPACT OF EVOLVED CHANGES IN GENE EXPRESSION AND CELLULAR PHENOTYPE ON PRIMATE EVOLUTION, Trisha Zintel, Molecular and Cellular Biology

Dissertations from 2019

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ENGINEERING OF AN ANTIBODY-CONJUGATED NANOGEL PLATFORM FOR TARGETED DRUG DELIVERY TO T LYMPHOCYTES, Mine Canakci, Molecular and Cellular Biology

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ENHANCING NANOPORE BASED BIOSENSENING TECHNOLOGY USING PORE FORMING PROTEINS, Christina M. Chisholm, Molecular and Cellular Biology

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CHARACTERIZATION OF β-2-MICROGLOBULIN PRE-AMYLOID OLIGOMERS AND THEIR ROLE IN AMYLOID INHIBITION, Tyler M. Marcinko, Molecular and Cellular Biology

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ENVIRONMENTAL RISK FACTORS FOR INFLAMMATORY BOWEL DISEASE: TRICLOSAN AND OTHER CONSUMER ANTIMICROBIALS, Katherine Z. Sanidad, Molecular and Cellular Biology

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Let-7 MiRNAs Program The Fate Of CD8 T Cells, Alexandria Wells, Molecular and Cellular Biology

Dissertations from 2018

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TARGETED LOCALIZATION OF MICROTUBULE-SEVERING ENZYMES TO CREATE NEW LOCAL TOOLS TO STUDY CELL DIVISION, Siddheshwari Advani, Molecular and Cellular Biology

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MECHANISM OF REGULATION OF KINESINS EG5 AND KIF15 BY TPX2, Sai Keshavan Balchand, Molecular and Cellular Biology

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EXAMINING sHSP-SUBSTRATE CAPTURE AND CHAPERONE NETWORK COORDINATION THROUGH CROSS-LINKING, Keith Ballard, Molecular and Cellular Biology

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REGULATION OF EXPRESSION OF THE  T CELL WC1 CO-RECEPTOR AND PATTERN RECOGNITION RECEPTOR MULTIGENE FAMILY, Payal Damani-Yokota, Molecular and Cellular Biology

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Structural studies of acid alpha glucosidase and Pompe disease, Derrick Deming, Molecular and Cellular Biology

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The Role of the Metallochaperone HypA in the Acid Survival and Activities of Nickel Enzymes in Helicobacter pylori, Heidi Hu, Molecular and Cellular Biology

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IDENTIFYING FUNCTIONAL COMPONENTS OF THE ENDOPLASMIC RETICULUM QUALITY CONTROL AND DEGRADATION FACTOR EDEM1, Lydia Lamriben, Molecular and Cellular Biology

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Motor Protein Regulation in Mammalian Mitosis, Barbara Mann, Molecular and Cellular Biology

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EPIGENETIC REGULATION OF GENOMIC IMPRINTING DURING EARLY MAMMALIAN EMBRYONIC DEVELOPMENT, Chelsea Marcho, Molecular and Cellular Biology

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Cadherin-11 Ectodomain Signaling in Cranial Neural Crest Migration, Ketan Mathavan, Molecular and Cellular Biology

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STUDIES OF DYNEIN ANCHORING PROTEIN IN BUDDING YEAST SACCHAROMYCES CEREVISIAE, Safia Omer, Molecular and Cellular Biology

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Defining and Manipulating the Function of Protein Kinase C-theta in Graft versus Host Responses, Emrah Ilker Ozay, Molecular and Cellular Biology

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EXTRINSIC AND INTRINSIC FACTORS IN LIVER DEVELOPMENT, Amrita Palaria, Molecular and Cellular Biology

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Studies on the P. aeruginosa T3S translocon assembly: interaction of PopD with membranes, Yuzhou Tang, Molecular and Cellular Biology

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CANONICAL NOTCH SIGNALING POSITIVELY REGULATES MIR-155 TRANSCRIPTION IN A NFκB-DEPENDENT MANNER, Joe Torres, Molecular and Cellular Biology

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CLPXP FUNCTIONS IN CAULOBACTER AS A UNIVERSAL AND SPECIES-SPECIFIC PROTEASE, Robert Vass, Molecular and Cellular Biology

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CHARACTERIZATION OF SHE1 SPINDLE ROLE USING CEULLULAR, BIOCHEMICAL, AND BIOPHYSICAL METHODS, Yili Zhu, Molecular and Cellular Biology