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Molecular and Cellular Biology Dissertations Collection

Dissertations from 2005 2005

The HFD of Cse4p is sufficient for a functional centromere specific nucleosome: An investigation into kinetochore formation on cen DNA, Lisa M Morey

Microtubule dynamics and behavior during the assembly and disassembly of mammalian mitotic spindles, Nasser M Rusan

Multiple roles for hedgehog signaling in zebrafish pituitary development, Jennifer L Sbrogna

Cloning and functional characterization of the zebrafish mutation belladonna, Anandita Seth

The action of T- and CS -syndrome pyrethroids on voltage-sensitive calcium channels in rat brain, Steven B Symington

EGFR expression and activation in bovine cumulus cells and EGFR intramolecular regulation through interactions between tyrosines, Zhong Zhao

Receptor clusters and dynamics in kinase regulation in bacterial chemotaxis, Li Zhi

Dissertations from 2004 2004

Estrogen and progesterone regulate p53 activity in the mouse mammary epithelium through transforming growth factor β dependent pathways, Klaus A Becker

Notch-1 regulates IFN-γ secretion through activation of NF-κB, Sridevi Gottipati

NIH 3T3 fibroblast adhesion to a fibronectin substrate: The role of the arachidonic acid signaling pathway, Joffre Angelo Green

Drosophila Wnt-1/Wingless undergoes a hydrophobic modification and is targeted to lipid rafts for secretion, a process that requires Porcupine, Xiaoling Hill

The role of Notch in T cell activation and development, Amy Marie Laws

Dietary phenolics for chemoprevention, Patrick P McCue

Formation and plasticity of glutamatergic synapses: Characterization of the roles of beta-amyloid precursor protein, scribble, and wingless at the Drosophila neuromuscular junction, Mary C Packard

Understanding the allosteric mechanism of the Escherichia coli Hsp70 molecular chaperone, DnaK, Renuka Sivendran

Using the mouse egg as a model system for the study of intracellular calcium signaling mechanisms, Jeremy T Smyth

Dissertations from 2003 2003

Cyclooxygenase and cyclic AMP -dependent protein kinase regulate actin organization and cell motility, Honor L Glenn

A new strategy for RNA structure probing in vivo: Targeting methylation small nucleolar RNPs to new sites in ribosomal RNA, Ben Liu

Identification and characterization of cuticular collagens in the human filarial parasite Onchocerca volvulus, Wen Li

Characterization and analysis of the cuticlin gene family of the human parasite Onchocerca volvulus, Michelle Renee Lizotte-Waniewski

The role of N -linked glycans in protein quality control in the early secretory pathway, Sherri L Svedine

When stress is good: Exercise and stress protein responses in mice and humans, Heather Sue Thompson

The role of oxidative stress in apoptosis, Noriko Tonomura

Overlapping and distinct functions for Gli proteins: Key mediators of hedgehog signaling in cell specification during embryonic development, Oksana V Tyurina

Acheron, a novel regulator of myoblast differentiation, Zhaohui Wang

Dissertations from 2002 2002

Studies of the complex of ribosomal protein L1 with its binding site in 23S rRNA: Modification -interference, mutagenesis and crosslinking, Denis Drygin

Diversification of the bovine primary immunoglobulin heavy chain repertoire: Ontological and hypermutational analyses in fetal and neonatal animals, Stephen Mark Jackson

Two new requirements for producing normal ribosomes: (I) A novel helicase is needed for snoRNP biogenesis, and; (II) Pseudoridine modifications in the reaction center are important for ribosome function, Thomas H King

Characterization of arachidonic acid -mediated signal transduction in regulation of NIH -3T3 cell adhesion to extracellular matrix, Rebecca A Stockton

Dissertations from 2001 2001

Structural and functional characterization of the unique N-terminus of Cse4p, A histone H3-like protein at the Saccharomyces cerevisiae centromere, Yinhuai Chen

Cloning and characterization of GUKHolder, a novel synaptically expressed protein that interacts with Discs -Large and SCRIBBLE at the Drosophila neuromuscular junction, L. Sian Gramates

Death associated lepidopteran DALP, and its mammalian ortholog Hic-5, act as negative regulators of muscle differentiation, Yanhui Hu

Structural changes between signaling states of bacterial chemoreceptors probed by solid -state NMR and hydrogen exchange, Owen James Murphy

Biosynthetic introduction of aryl bromide functionality into proteins, Nandita Sharma

Analysis of the interaction between the epidermal growth factor receptor and actin, Jun Tang

Analysis of programmed cell death in Drosophila, John Patrick Wing

Identification of genes affected by fetal alcohol exposure during brain development, Jun Yang

Dissertations from 2000 2000

Maternal thyroid hormone regulates gene expression in the fetal rat brain, Amy Louise Skinner Dowling

The effect of dominant negative EGR-1 and hyperbaric oxygen on immune cell apoptosis, Bishu Jeet Ganguly

Replication and 3'-end repair of a subviral RNA associated with turnip crinkle virus, Hancheng Guan

Inhibition of protein synthesis in Escherichia coli by expression of RNAs containing multiple ribosome binding sites, Mary V Mawn

The localization, differential expression, and potential immunological role of thioredoxin peroxidase -2 (TPX-2) in the filarial parasite Brugia malayi, Lori J Saunders

The role of cell cycle progression and cyclin -dependent kinase 2 in thymocyte negative selection, Jennifer Lynn Trimble

Symptom modulation by subviral RNAs associated with turnip crinkle virus, Jianlong Wang

Towards the isolation of esterase and amidase catalytic antibodies: Examination of germinal center diversity by cloning and sequence analysis of genes encoding monoclonal antibodies elicited by a transition state analogue, Zhongde Wang

Dissertations from 1999 1999

Calcium regulation in Tradescantia virginiana: Roles for involvement of inositol 1,4,5-trisphosphate and cyclic ADP-ribose, Anthony Lyndon DePass

Characterization of the yolk protein lipovitellin and its developmental fate in embryos and larvae of winter flounder, Pleuronectes americanus, Ruth C Hartling

Role of lipid signalling pathways in an intra and an extracellular phenomenon, Banafshe Larijani

Regulation of the actin cytoskeleton in the pollen tube, Luis Vidali

Androgen modulation of neurotrophic factor action: A possible mechanism for sexually dimorphic neural development, Jun Xu

Dissertations from 1998 1998

Toward an antibody peptidase: Mechanistic studies of peptide-bond hydrolysis, Rebecca A. R Bryant

The role of mitochondria and proteasomes in T cell apoptosis, Lisa Marie Grimm

Modulation of epidermal growth factor receptor function by mutations within the actin-binding domain, Michael Ray Holbrook

The major function of eukaryotic small nucleolar RNAs is nucleotide modification in ribosomal RNA, Jingwei Ni

Alternative splicing of MDM2 during breast tumorigenesis and mammary gland development, Jan Pinkas

Box C/D small nucleolar RNAs: Biogenesis, structure and utilization for in vivo ribozyme studies, Dmitry A Samarsky

Understanding mitochondrial biogenesis through gene relocation, Marie Elise Sanchirico

CSE1, an essential yeast gene required for cell cycle progression, encodes a nuclear transport factor, Andrew J Schroeder

Molecular and genetic characterization of the 10.4 kDa cytoplasmic dynein light chain and its effects on the neuroanatomy of Drosophila, Debbie Marie Statton

Dissertations from 1997 1997

Effects of amino acid substitution on chain packing in genetically engineered periodic polypeptides, Eric Jim-Bai Cantor

Characterization and phosphorylation of an MPM-2 reactive sperm protein complex involved in zygotic aster formation, Richard Peter Duncan

Characterization of midline uncoordinated, a mutation affecting behavior and neuroanatomy in Drosophila, Jennifer Ellen Klenz

Characterization of yeast U14 snoRNA interactions required forrRNA processing, and development of a novel in vivorDNA system for dissecting ribosome biogenesis, Wen-Qing Liang

wingless signaling in development of the Drosophila optic ganglia, Xiwei Wang

Cloning and characterization of a new gene involved in lymphocyte activation, Meng Zhang

Dissertations from 1996 1996

Molecular approaches for the construction of integrated physical and genetic maps, Sakthikumar Ambady

Seeking the primary sense: A biochemical and biophysical study of the signaling mechanism of bacterial chemotaxis, Jiayin Li

Cloning and characterization of thioredoxin peroxidase (TPx) in Onchocerca volvulus, Wenhong Lu

Dissertations from 1995 1995

Follicle cell calmodulin: transcript accumulation in vitellogenic follicles of Blattella germanica is regulated by juvenile hormone, Anand R Iyengar

Studies of bovine B cell development, Chuen-Lei Parng

Dissertations from 1994 1994

B cell development and immunoglobulin genes in cattle, Susan A Hansal

Dissertations from 1992 1992

Topography of transfer RNA binding sites on the Escherichia coli ribosome : a cross-linking study using azidoadenosine-substituted transfer RNAs/, Lee A. Sylvers, Molecular and Cellular Biology