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Document Type

Open Access

Degree Program

Electrical & Computer Engineering

Degree Type

Master of Science (M.S.)

Year Degree Awarded

2012

Month Degree Awarded

September

Keywords

THz, medical imaging, reflectivity, refractive index, FDTI, breast cancer

Abstract

This project evaluates the ability of terahertz (THz) radiation to differentiate cancerous from non-cancerous human breast lumpectomy and mastectomy tissue. This is done by aiming a narrow-band THz beam at medical samples and measuring reflected power. THz images of specimens from Breast Conservation Surgery (BCS) were created using a gas laser source and mechanical scanning. The design and characterization of this system is discussed in detail. The images were correlated with optical histological micrographs of the same specimens and discrimination values of more than 70% were found for five of the six samples using Receiver Operating Characteristic (ROC) analysis.

First Advisor

Sigfrid K. Yngvesson

Second Advisor

Paul R. Siqueira

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