We describe the structure of all codimension-2 lattice configurations A which admit a stable rational A-hypergeometric function, that is a rational function F all the partial derivatives of which are nonzero, and which is a solution of the A-hypergeometric system of partial differential equations defined by Gel′ fand, Kapranov, and Zelevinsky. We show, moreover, that all stable rational A-hypergeometric functions may be described by toric residues and apply our results to study the rationality of bivariate series the coefficients of which are quotients of factorials of linear forms.