Publication:
Dietary B Vitamins and Depression in Persons with Human Immunodeficiency Virus Infection: The Positive Living with HIV (POLH) Study

dc.contributor.authorPoudel-Tandukar, Kalpana
dc.contributor.departmentUniversity of Massachusetts Amherst
dc.date2023-09-23T18:13:31.000
dc.date.accessioned2024-04-26T19:37:41Z
dc.date.available2017-06-19T00:00:00Z
dc.date.issued2016-01-01
dc.description.abstractB vitamins have beneficial roles in mental health functional impairments; however, research on the role of B vitamins in depression among HIV-infected persons is limited. This study assessed the association between dietary B vitamin intake and depressive symptoms in a cohort of HIV-infected persons. A cross-sectional survey was conducted among 314 HIV-infected persons (180 men and 134 women) aged 18 to 60 y residing in the Kathmandu, Nepal. The Beck Depression Inventory-I was used to measure depression, with a cutoff score of 20 or higher. Dietary intake was assessed using two nonconsecutive 24-h dietary recalls. The relationships between B vitamins and depressive symptoms were assessed using multiple logistic regression analysis. Twenty-six percent participants (men: 23%; women: 29%) were depressed. More than two thirds of participants’ B vitamins intake were below the estimated average requirements (EAR) level. Low intake of riboflavin was associated with an increased risk of depression in women but not in men. Multivariate OR (95% CI) for depression in the first, second, and third tertiles of riboflavin in total participants were 1 (reference), 0.87 (0.46–1.64), and 0.49 (0.24–0.98), respectively (p for trend = 0.048) and in women were 1 (reference), 0.94 (0.36–2.40), and 0.23 (0.07–0.77), respectively (p for trend = 0.020). No clear associations were seen between other B vitamins and depressive symptoms in either sex. Low intake of riboflavin was independently associated with an increased risk of depressive symptoms in all participants and in HIV-infected women. Further prospective studies are warranted to confirm the role of vitamin B vitamins in depressive symptoms among HIV-infected persons.
dc.description.pages388-396
dc.description.sponsorshipUMass SOAR Fund
dc.identifier.urihttps://hdl.handle.net/20.500.14394/38205
dc.relation.ispartofJournal of Nutritional Science and Vitaminology
dc.relation.urlhttps://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1221&context=nursing_faculty_pubs&unstamped=1
dc.rightsUMass Amherst Open Access Policy
dc.source.issue62
dc.source.statuspublished
dc.subjectB vitamins
dc.subjectdepression
dc.subjectdiet
dc.subjectHIV
dc.subjectriboflavin
dc.subjectNursing
dc.subjectPublic Health and Community Nursing
dc.titleDietary B Vitamins and Depression in Persons with Human Immunodeficiency Virus Infection: The Positive Living with HIV (POLH) Study
dc.typearticle
dc.typearticle
digcom.contributor.authorisAuthorOfPublication|email:kalpana@nursing.umass.edu|institution:University of Massachusetts Amherst|Poudel-Tandukar, Kalpana
digcom.date.embargo2017-06-19T00:00:00-07:00
digcom.identifiernursing_faculty_pubs/221
digcom.identifier.contextkey10318405
digcom.identifier.submissionpathnursing_faculty_pubs/221
dspace.entity.typePublication
relation.isAuthorOfPublicationa428539a-df57-451a-821e-dc26672842f0
relation.isAuthorOfPublication.latestForDiscoverya428539a-df57-451a-821e-dc26672842f0
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