My dissertation proposes an expansion of the term ‘science’ as it has been historically framed during the European Renaissance through the seventeenth century and beyond, that is science as the study of the natural and physical world through empirical reasoning and experimentation. This singular understanding of science worked in tandem with European imperial conquest throughout the Caribbean. Thus, not only did imperialism attempt to dehumanize Caribbean people but the European scientific method attempted to eclipse other forms of knowledge that was used by Caribbean people to understand each other, their region, and their place in the world. Through my close reading of seven novels by six Caribbean science fiction writers, Karen Lord, Nalo Hopkinson, Pedro Cabiya, Anthony Joseph, Imam Baksh, and Rita Indiana, and one novel by the American Afrofuturist writer Octavia Butler, I redefine science away from the singular, that is European, origin and toward a cultural science, that is informed as much by reasoning and experience but that differs in its strict adherence to empiricism and experimentation. To help ground my argument of a cultural science, I use the term ‘scientia’, the etymological origin of the word ‘science’. Where ‘scientia’ originally referred to knowledge and awareness gained through experience, I coin the term ‘Caribbean scientia’ to specify a mode of Caribbean knowledge and awareness gained through experience and translated through storytelling, specifically stories that borrow concepts and images commonly found in science fiction such as intergalactic species, spaceship, and time travel. Through the questioning of the foundations of science through science fiction, I offer a different lens to interpret narratives of futurity as themselves examples of knowledge production which allow us to rethink what Caribbean people know and how that knowledge is used to interpret the spaces, physical and metaphysical, that they inhabit.