Resource selection is a critical aspect of wildlife ecology, and understanding how animals interact with human-associated resources is of increasing importance as urbanization rapidly increases. This study investigates the resource selection patterns of Massachusetts black bears in relation to human-associated resources across various seasons and reproductive statuses. This study used black bear locations and availability of resources within bear home ranges to investigate selection using resource selection functions. Our findings reveal distinct seasonal resource utilization patterns among black bears. Spring and fall show increased use of areas characterized by human-development, with a notable preference for agricultural resources during the fall season. The proximity to human structures significantly influences resource selection, particularly during spring and fall. Bears consistently avoid locations with a high percentage of building structures throughout the year. This study did not detect a statistically significant difference in land cover selection between bears with newborn cubs and those without cubs, indicating that reproductive status may not substantially impact resource selection at this scale. For both reproductive statuses, the selection probability rises as the distance to human structures increases. Bears, both with and without cubs, are less likely to select locations as the percentage of building structures increases. These findings provide a foundation for future research endeavors, where the integration of bear-specific information into predictive models will enhance resource selection predictions. This knowledge contributes to effective wildlife management and conservation strategies, especially in regions characterized by significant human-bear interactions.