Purpose: Asthma is a chronic condition that affects millions of people, many of whom are children. There is a significant amount of evidence detailing best evidence step-by-step treatments based on severity, yet many children still have uncontrolled asthma. The comprehensive management of asthma is essential to improve health outcomes for children with asthma. Methods: This project evaluated the implementation of the Global Initiative for Asthma (GINA) guidelines and assessed the barriers and facilitators present in a pediatric clinic which impact care delivery. This project Involved the implementation of an educational intervention based on the GINA guidelines to facilitate a team-based approach to asthma management. Results: Eight staff members participated in the project. The most significant changes were 75% of staff reported an increase in their knowledge of the GINA guideline recommendations, staff reported a 25% increase in team member participation in asthma care, and staff reported a 12.5% increase in their feelings of support for the use of team-based implementation of the GINA guidelines from leadership. The results of this quality improvement project support the use of Roger’s Diffusion of Innovations model as a theoretical framework to support implementation of a team-based approach to the use of the GINA guidelines in a pediatric clinic. Conclusions: Education on evidence-based guidelines improves clinic staff knowledge and utilization of the guidelines. However, factors such as leadership involvement, clinic infrastructure, and standardized clinical tools are essential for successful implementation of a team-based approach to asthma management.