The pressure from high population density leads to the creation of high-rise structures within urban areas. Consequently, the design of facilities which confront the challenges of emergency evacuation from high-rise buildings become a complex concern. This paper proposes an embedded program which combines a deterministic (GMAFLAD) and stochastic model (M/G/C/C State Dependent Queueing model) into one program, GMAF_MGCC, to solve an evacuation problem. An evacuation problem belongs to Quadratic Assignment Problem (QAP) class which will be formulated as a Quadratic Set Packing model (QSP) including the random flow out of the building and the random pairwise traffic flow among activities. The procedure starts with solving the QSP model to find all potential optimal layouts for the problem. Then, the stochastic model calculates an evacuation time of each solution which is the primary decision variable to figure the best design for the building. Here we also discuss relevant topics to the new program including the computational accuracy and the correlation between a successful rate of solving and problems’ scale. This thesis examines the relationship of independent variables including arrival rate, population and a number of stories with the dependent variable, evacuation time. Finally, the study also analyzes the probability distribution of an evacuation time for a wide range of problem scale.