This study is designed to examine the perception of residents, including second home owners of the province of Mersin about their general and tourism specific attitudes of the proposed nuclear power plant (NPP) location and assess the degree to which if there would be variations of perceptions within the local population about the construction of NPP. The study revealed that elder and more educated individuals have stronger opposition attitudes about the construction of the proposed NPP. However, the overall result indicates a matter of degrees of opposition that may need to be managed or mitigated should the project is implemented.