This is not a manifesto, nor is it a prescriptive call for a new, decolonial, or decolonized science and technology studies (STS). Instead, our critical perspectives in this issue are propositional offerings. We aim to provoke questions about how science and technology studies might intersect with decolonizing or decolonial practices and scholarship, and what kinds of openings these intersections may or may not provide. We offer these reflections as invitations to think with us and to consider the worlds in which we live and work. They are entries into a conversation that, of course, does not start or end with us, but rather draws upon multiple intellectual genealogies and particular struggles and colonial histories.